Assessment of diagnostic value of ‘Human Epididymis Factor 4 (HE4)’ in women with adnexal masses
نویسندگان
چکیده
منابع مشابه
Determination of reference intervals of serum levels of human epididymis protein 4 (HE4) in Chinese women
BACKGROUND To determine reference intervals for serum levels of human epididymis protein 4 (HE4) in Chinese women. METHODS In this multicenter (n = 9) study, 618 healthy women, 767 patients with non-malignant diseases, and 951 patients with malignant tumors were enrolled. Serum levels of HE4 were measured in all patients using electrochemiluminescence immunoassays. The influence of age, menop...
متن کاملHuman epididymis protein 4 (HE4) in benign and malignant diseases.
BACKGROUND Human epididymis protein 4 (HE4) is described as a useful new biomarker in ovarian cancer. As HE4 is neither tumor nor organ specific, we intensively investigated the occurrence of this protein in female and male patients with various benign and malignant diseases in order to avoid misinterpretation and to identify potential additional clinical relevance. METHODS We retrospectively...
متن کاملEvaluation of diagnostic accuracy of RMI and ROMA indices in comparison to HE4 and CA125 parameters for estimating the risk of malignancy of adnexal masses.
Background: Ovarian cancer is the fifth leading cancer-related cause of death in women worldwide and is often diagnosed at advanced stages. Regarding the low sensitivity and specificity of the currently available diagnostic techniques, in the present study, we aimed to evaluate the accuracy of RMI and ROMA indexes and comparing these two indexes with CA-125 and HE4 parameters for the diagnosis ...
متن کاملThe diagnostic accuracy of two human epididymis protein 4 (HE4) testing systems in combination with CA125 in the differential diagnosis of ovarian masses.
BACKGROUND Cancer antigen 125 (CA125) is the best known single tumor marker for ovarian cancer (OC). We investigated whether the additional information of the human epididymis protein 4 (HE4) improves diagnostic accuracy. METHODS We retrospectively analyzed preoperative sera of 109 healthy women, 285 patients with benign ovarian masses (cystadenoma: n=78, leimyoma: n=66, endometriosis: n=52, ...
متن کاملValue of MRI in Characterizing Adnexal Masses.
Magnetic resonance imaging (MRI) increases the specificity of imaging evaluation for adnexal masses, especially when they are indeterminate on ultrasound, very large or when further imaging is required to establish tissue characteristics. This article is a pictorial essay describing the value of MRI in characterizing adnexal masses.
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ژورنال
عنوان ژورنال: Pamukkale Medical Journal
سال: 2020
ISSN: 1309-9833
DOI: 10.31362/patd.712419